Simvastatin EG 40 mg x 100 Tablets: Treats cholesterol
Reduction of cardiovascular mortality and morbidity in patients with a proven cardiovascular pathology of atherosclerotic origin or diabetes, with normal or high cholesterol in addition to the effect of the correction of other risk factors and other cardioprotective treatments.
Initial dosage: 10 to 40 mg per day.
Maximum dosage: 80 mg per day.
CHILDREN AND ADOLESCENTS FROM 10 TO 17 YEARS OLD WITH HETEROZYGOTE FAMILY HYPERCHOLESTEROLEMIA
Usual recommended starting dose: 10 mg, once a day.
Maximum recommended dose: 40 mg per day.
Homozygous familial hypercholesterolemia
Recommended initial dosage: 40 mg per day.
Usual dosage: 20 to 40 mg per day.
Severe renal impairment (creatinine clearance <30 ml / min): administer doses above 10 mg / day with caution.
A dose adjustment is also indicated in case of concomitant treatment with certain fibrates, amiodarone, amlodipine, verapamil or diltiazem.
Administer in 1 single dose, in the evening.
Can be taken with or without food.
If dosage adjustment: follow intervals of at least 4 weeks.
If combined with ion exchange resins / bile acid chelators: simvastatin must be taken> 2 hours before or> 4 hours after these resins.
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